Extemporaneous Compounding

A Pilot Stability Study of Dehydroepiandrosterone Rapid-dissolving Tablets Prepared by Extemporaneous Compounding.

Dehydroepiandrosterone supplementation is used to treat a variety of conditions. Rapid-dissolving tablets are a relatively novel choice for compounded dehydroepiandrosterone dosage forms. While rapid-dissolving tablets offer ease of administration, there are uncertainties about the physical and chemical stability of the drug and dosage form during preparation and over long-term storage. This st...

Extemporaneous compounding of oral liquid dosage formulations and alternative drug delivery methods for anticancer drugs.

Oncology pharmacists face a constant challenge with patients who cannot swallow oral anticancer drugs, making extemporaneous oral liquid preparation a requirement. Improper extemporaneous preparation of these agents, especially with the traditional chemotherapy with a narrow therapeutic index, may increase the risk of over- or underdosing. In community pharmacies, multiple barriers exist that p...

Modeling Extemporaneous Elaboration

Intelligent problem solving systems must be able to express their results in a coherent and flexible manner. One way this can be done is by eztemporaneous elaboration, the method of language production that underlies more skilled tasks such as explanation. This paper outlines a computational model for extemporaneous elaboration that is implemented in a computer model called Extemper, shows exam...

Extemporaneous Isoniazid Mixture: Stability Implications

Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions

Dissolution studies have become matter of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process. As occurs with solid oral dosage forms, heterogeneous disperse systems (suspensions) could also have some problems with their in vitro dissolution. The dissolution behavior of four different brands of cefadroxil extemporaneous suspensions ava...